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RESULTSAntioxidant activities of CP. CP extracted from commercialcocoa powder contained 468 mg/g gallic acid–equivalentphenolics and 413 mg/g epicatechin-equivalent flavonoids.Similar to our previous observations with pure phenolic phytochemicals(28), CP exhibited a dose-dependent free... 顯示更多 RESULTS Antioxidant activities of CP. CP extracted from commercial cocoa powder contained 468 mg/g gallic acid–equivalent phenolics and 413 mg/g epicatechin-equivalent flavonoids. Similar to our previous observations with pure phenolic phytochemicals (28), CP exhibited a dose-dependent free radicalscavenging activity as determined by both ABTS and DPPH radical-scavenging assays (Fig. 1A). The elevation of xanthine oxidase activity and generation of the superoxide anion during the promotional phase of tumorigenesis have been reported previously (18).CP dose-dependently inhibited xanthine oxidase activity (Fig. 1B). Treatment with CP also suppressed the TPAinduced generation of superoxide anion in cultured HL-60 cells (Fig. 1B) without affecting cell viability (data not shown). CP inhibits TPA-induced ear edema and COX-2 expression in mouse skin. Intragastric administering of CP significantly decreased TPA-induced ear edema by 58 and 87% at doses of 40 and 200 mg/kg body weight, respectively (P , 0.01, Table 1). Oral administering of CP at 0.5 h prior to topical application of TPA on the shaved back of female ICR mice resulted in a dose-dependent reduction in TPA-induced COX-2 expression (Fig. 2). 更新: Inhibitory effects of CP on TPA-induced DNA binding activity of NF-kB, nuclear translocation of p65, and degradation of IkBa. 更新 2: 你好~因為我貼不下@@..可以給我你的mail嗎?我把原文mail給您~~翻好之後我給你點數^^

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結果CP 的抗氧化活動。CP 從商業可可粉被提取包含了468 mg/g 五倍子酸等效酚醛樹脂和413 個mg/g 表兒茶素等效黃酮類化合物。相似與我們的早先觀察與純淨的酚醛phytochemicals (28), CP 依照由ABTS 和DPPH 根本換氣確定陳列了dose-dependent 自由radicalscavenging 的活動分析用試樣(圖1A) 。黃嘌呤oxidase 活動的superoxide 陰離子的海拔和世代在增進階段tumorigenesis 期間早先被報告了(18).CP 藥量依賴禁止了黃嘌呤oxidase 活動(圖1B) 。治療以CP 並且壓制了superoxide 陰離子的TPAinduced 世代在被開化的HL-60 細胞(圖裡1B) 沒有影響細胞生活能力(資料沒被顯示) 。CP 禁止TPA 導致的耳朵腫鼓和COX-2 表示在老鼠皮膚。Intragastric 執行CP 極大減少了TPA 導致的耳朵腫鼓58 和87% 在40 和200 mg/kg 體重藥量, 各自地(P, 0.01, 表1) 。口頭執行CP 在0.5 h 在TPA 的典型應用之前在母ICR 老鼠被刮的後面導致對TPA 導致的COX-2 表示的dose-dependent 減少(圖2) 。 大慨是這樣 2006-09-30 09:32:55 補充: 你直接去奇摩的字典查就好ㄌ奇摩那邊有一ㄍ段落翻譯阿~

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